Invitrogen™ MPP5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5121766

Product Code. 17743164

Description

MPP5 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

MPP5 (Membrane Protein, Palmitoylated 5) plays a critical role in neurogenesis and hematopoiesis. This protein is crucial for establishing and maintaining cell polarity in epithelial cells and neurons. It is involved in the Par-3 complex, which contributes to maintaining tight junctions in epithelial cells. Mutations in MPP5 have been associated with severe neurologic impairments, including global developmental delay (GDD) and behavioral changes. In animal models, MPP5 is highly involved in the early differentiation of multipotent progenitors and supports long-term lineage-specific contributions, primarily in myeloid and lymphoid cells. MPP5 variants disrupt normal cellular function, leading to profound developmental and functional abnormalities.

Specifications

• Antigen: MPP5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MPP5
• Gene Alias: 3830420B02Rik; AI255216; AI644496; FLJ12615; MAGUK p55 subfamily member 5; membrane palmitoylated protein 5; membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 5); membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); MPP5; palmitoylated 5; PALS1; protein associated with Lin Seven 1; protein associated with Lin-7 1; stardust
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 56217, 64398
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: Q8N3R9, Q9JLB2
• Gene Symbols: MPP5
• Immunogen: Recombinant protein Membrane Protein, Palmitoylated 5. The antigen corresponds to amino acid range 455-675 of the target protein.
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG