Invitrogen™ Monkey IL-6R ELISA Kit

Monkey IL-6R quantitates monkey IL-6R in serum, plasma, supernatant.

Brand:  Invitrogen™ EP14RBX10

Product Code. 18567824

Description

Monkey IL-6R quantitates monkey IL-6R in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant monkey IL-6R.

Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.

Specifications

• Accession Number: CD126; CD126 antigen; gp80; IL-6 Receptor; il-6 receptor alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL6Q; Il6r; IL-6 R; IL-6 R 1; IL-6 R subunit alpha; IL6R1; IL-6 R-1; Il6ra; IL-6 RA; IL-6 R-alpha; IL6RQ; ILN; Interleukin; interleukin 6 receptor; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991
• Assay Sensitivity: 12 pg/mL
• Product Type: ELISA
• For Use With (Equipment): Colorimetric Microplate Reader
• Intraassay CV: <10%
• Label or Dye: HRP
• Regulatory Status: Research Use Only
• Storage Requirements: 2°C to 8°C
• Test Time: 1 hr 20 min

• Assay Range: 12 to 3,000 pg/mL
• Conjugate: Biotin
• Sample Type: Plasma
• Interassay CV: <12%
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Quantity: 10 x 96 Tests
• Sample Volume: Supernatant, 50 µL; Plasma, 50 µL; Serum, 50 µL
• Target: IL-6 Receptor (CD126)
• Total Assay Time: 4 hr 45 min