missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Analysis Products
  4. Cell Based Assays
  5. Cell Function Reagents and Kits
  6. 11550756

Invitrogen™ Transferrin From Human Serum, Alexa Fluor™ 488 Conjugate

Product Code. 11550756
Click to view available options
Quantity:
5 mg
Unit Size:
5mg
This item is not returnable. View return policy
For Research Use Only. All usage must comply with product instructions.
 

Product Code. 11550756

Brand: Invitrogen™ T13342

Please to purchase this item. Need a web account? Register with us today!

Edge
304.85 GBP valid until 2025-12-19
BEST PRICE on Promo! Use promo code "24092" to get your promotional price.
This item is not returnable. View return policy
For Research Use Only. All usage must comply with product instructions.
 

Description

Transferrin is a monomeric serum glycoprotein that binds to a specific receptor on the surface of vertebrate cells and delivers up to two Fe3+ atoms via receptor-mediated endocytosis—our labeled LDL complexes are useful tools for studying this phenomenon.

Transferrin is a monomeric serum glycoprotein (∼80,000 daltons) that binds to a specific receptor on the surface of vertebrate cells and delivers up to two Fe3+ atoms via receptor-mediated endocytosis—our labeled LDL complexes are useful tools for studying this phenomenon. Once iron-carrying transferrin proteins are inside endosomes, the acidic environment favors dissociation of iron from the transferrin–receptor complex. Following the release of iron, the apotransferrin is recycled to the plasma membrane, where it is released from its receptor to scavenge more iron. Fluorescent transferrin conjugates can therefore be used with fluorescent LDL to distinguish the lysosomally directed and recycling endosomal pathways.

These experiments are typically performed by adding fluorescently labeled transferrin to cultured cells and analyzing them by microscopy. We offer a biotinylated transferrin conjugate and more than 10 fluorescent versions.

Consult user Manual for solubility instructions.

Transferrin Specifications:
• Label (Ex/Em): Alexa Fluor™ 488 (495/519)
• Amount: 15 mg solid (contains 5 mg of transferrin conjugate)

Key Applications of Labeled Transferrin
Some of the many applications for labeled transferrin include:
• Image transferrin receptor dynamics using FRET
• Observe receptor trafficking in live cells by confocal laser-scanning microscopy
• Investigate events occurring during endosomal acidification
• Measure transferrin receptor binding affinity in mammals and parasites

Order Info

Shipping Condition: Room Temperature

TRUSTED_SUSTAINABILITY

Specifications

Content And Storage Store in freezer (-5°C to -30°C) and protect from light.
Detection Method Fluorescence
Product Type Transferrin
Dye Type Alexa Fluor Dyes
Form Solid
pH 7.2
Product Line Alexa Fluor
Quantity 5 mg
Shipping Condition Room Temperature
Excitation/Emission 495/519 nm
Protein Family Transferrin
Show More Show Less

For Research Use Only. Not for use in diagnostic procedures.

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.