MMP13 Rabbit anti-Human, Mouse, Rat, Zebrafish, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 18165-1-AP-20UL

Product Code. 16838224

Description

MMP13 (collagense 3) plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC, and ACAN. MMP13 cleaves tripal helical collagens, including type I, II, and III collagen - but has the highest activity with soluble type II collagen. It can degrade collagen type IV, XIV, and X. MMP13 plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization, and ossification. It is required for normal embryonic bone development and ossificaiton. Mutations affecting the gene can lead to spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.

Specifications

• Antigen: MMP13
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MMP13
• Gene Alias: CLG3, Collagenase 3, Matrix metalloproteinase 13, MMP 13, MMP13
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171052, 17386, 387293, 4322
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunoprecipitation, Immunofluorescence, Immunocytochemistry, Immunohistochemistry (Paraffin)
• Concentration: 0.27 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P23097, P33435, P45452
• Gene Symbols: Mmp13, mmp13a
• Immunogen: MMP13 Fusion Protein Ag12653
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Human, Zebrafish, Rat
• Product Type: Antibody
• Isotype: IgG