MMP13 Rabbit anti-Human, Mouse, Rat, Zebrafish, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16838224	Proteintech 18165-1-AP-20UL	20 μL
16828224	Proteintech 18165-1-AP-150UL	150 μL

Description

MMP13 (collagense 3) plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC, and ACAN. MMP13 cleaves tripal helical collagens, including type I, II, and III collagen - but has the highest activity with soluble type II collagen. It can degrade collagen type IV, XIV, and X. MMP13 plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization, and ossification. It is required for normal embryonic bone development and ossificaiton. Mutations affecting the gene can lead to spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.

Specifications

• Antigen: MMP13
• Applications: Western Blot, Immunoprecipitation, Immunofluorescence, Immunocytochemistry, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Mouse, Human, Zebrafish, Rat
• Gene Accession No.: P23097, P33435, P45452
• Gene ID (Entrez): 171052, 17386, 387293, 4322
• Immunogen: MMP13 Fusion Protein Ag12653
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: MMP13

• Concentration: 0.27 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: CLG3, Collagenase 3, Matrix metalloproteinase 13, MMP 13, MMP13
• Gene Symbols: Mmp13, mmp13a
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody