MKP-2 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1G1C12, Proteintech

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
16828145	Proteintech 66349-1-IG-20UL	20 μL
16818145	Proteintech 66349-1-IG-150UL	150 μL

Description

DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP4 inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus.

Specifications

• Antigen: MKP-2
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: dual specificity phosphatase 4, DUSP4, HVH2, MAP kinase phosphatase 2, MKP 2, MKP2, MKP-2, TYP, VH2
• Gene Symbols: Dusp4
• Isotype: IgG1
• Purification Method: Protein G
• Product Type: Antibody

• Clone: 1G1C12
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunofluorescence
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Rat, Human, Mouse, Pig
• Gene Accession No.: Q13115, Q62767, Q8BFV3
• Gene ID (Entrez): 100514374, 1846, 319520, 60587
• Immunogen: MKP-2 Fusion Protein Ag1206
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: DUSP4