MKP-2 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1G1C12, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66349-1-IG-150UL

Product Code. 16818145

Description

DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP4 inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus.

Specifications

• Antigen: MKP-2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q13115, Q62767, Q8BFV3
• Gene Symbols: Dusp4
• Immunogen: MKP-2 Fusion Protein Ag1206
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Pig, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: 1G1C12
• Conjugate: Unconjugated
• Gene: DUSP4
• Gene Alias: dual specificity phosphatase 4, DUSP4, HVH2, MAP kinase phosphatase 2, MKP 2, MKP2, MKP-2, TYP, VH2
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 100514374, 1846, 319520, 60587
• Content And Storage: -20°C
• Form: Liquid