Melanoma Associated Antigen (KBA.62) Antibody (KBA.62), Novus Biologicals™

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
18111918	Novus Biologicals NBP2-45285-0.02MG	0.02 mg
18119147	Novus Biologicals NBP2-45285-0.1MG	0.1 mg

Description

Ensure accurate, reproducible results in Immunohistochemistry (Paraffin), Immunofluorescence

Melanoma Associated Antigen (KBA.62) Monoclonal specifically detects Melanoma Associated Antigen (KBA.62) in Human samples. It is validated for Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

• Antigen: Melanoma Associated Antigen (KBA.62)
• Concentration: 0.2mg/mL
• Applications: Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Immunogen: Human KAL cells derived from lymph node metastasis of malignant melanoma
• Primary or Secondary: Primary
• Content And Storage: Store at 4C.

• Clone: KBA.62
• Dilution: Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Isotype: IgG1 κ
• Purification Method: Protein A or G purified
• Test Specificity: KBA.62 is a novel anti-melanoma antibody. It reacts positively against melanocytic tumors but not other tumors, thus demonstrating specificity and sensitivity. Moreover, it reacts positively against junctional nevus cells but not intradermal nevi, and against fetal melanocytes but not normal adult melanocytes. KBA.62 antibody is useful in identifying malignant melanomas. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, sarcomas, spindle cell carcinomas and various types of mesenchymal neoplasms. A keratin-negative, vimentin-rich neoplasm that immuno-reacts with antibody to S-100 protein and with KBA.62 antibody is, with rare exception, a melanoma. Anti-KBA.62 is a useful additional marker for melanoma, specifically in desmoplastic/spindle cell cases and in the context of micro-metastasis in sentinel lymph node.

For Research Use Only