MECR Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16883854	Proteintech 14932-1-AP-20UL	20 μL
16873854	Proteintech 14932-1-AP-150UL	150 μL

Description

The mitochondrial trans-2-enoyl-CoA reductase (MECR), was initially identified as nuclear receptor-binding factor 1 (NRBF1), which can interact with a multitude of nuclear hormone receptors in the presence of the respective ligands. MECR has been shown to be part of the mitochondrial fatty acid synthesis (FAS II) system and to catalyze the NAPDH-dependent reduction of 2-enoyl thioesters, generating saturated acyl-groups. Overexpression of this gene in transgenic mice can lead to cardiac abnormalities, suggesting that inappropriate expression of genes of FAS II can result in the development of hereditary cardiomyopathy.

Specifications

• Antigen: MECR
• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Mouse, Rat, Human
• Gene Accession No.: Q9BV79, Q9DCS3, Q9Z311
• Gene ID (Entrez): 26922, 29470, 51102
• Immunogen: MECR Fusion Protein Ag6738
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: MECR

• Concentration: 0.22 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: CGI 63, FASN2B, HsNrbf 1, MECR, NBRF1, NRBF 1, NRBF1
• Gene Symbols: MECR
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody