MECR Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 14932-1-AP-20UL

Product Code. 16883854

Description

The mitochondrial trans-2-enoyl-CoA reductase (MECR), was initially identified as nuclear receptor-binding factor 1 (NRBF1), which can interact with a multitude of nuclear hormone receptors in the presence of the respective ligands. MECR has been shown to be part of the mitochondrial fatty acid synthesis (FAS II) system and to catalyze the NAPDH-dependent reduction of 2-enoyl thioesters, generating saturated acyl-groups. Overexpression of this gene in transgenic mice can lead to cardiac abnormalities, suggesting that inappropriate expression of genes of FAS II can result in the development of hereditary cardiomyopathy.

Specifications

• Antigen: MECR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MECR
• Gene Alias: CGI 63, FASN2B, HsNrbf 1, MECR, NBRF1, NRBF 1, NRBF1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26922, 29470, 51102
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, Western Blot
• Concentration: 0.22 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9BV79, Q9DCS3, Q9Z311
• Gene Symbols: MECR
• Immunogen: MECR Fusion Protein Ag6738
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat, Human
• Product Type: Antibody
• Isotype: IgG