Ly-6A/E (Sca-1) Rat anti-Mouse, Clone: D7, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-5981-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15257657

Quantity Price
1 £ 133.91 / 500µg
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Monoclonal or Polyclonal Monoclonal
Host Species Rat
Clone D7
Antigen Ly-6A/E (Sca-1)
Quantity 500μg
Isotype IgG2a
Regulatory Status RUO
Concentration 0.5mg/mL
Primary or Secondary Primary
Conjugate Unlabeled
Format Purified
Applications Flow Cytometry
Applications Immunoprecipitation
Applications Western Blotting
Species Reactivity Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C.

The D7 monoclonal antibody reacts with mouse Sca-1, an 18kDa member of the Ly-6 family of GPI-linked surface proteins. D7 reacts with both Ly-6E.1 and Ly-6A.2 molecules expressed by mouse hematopoietic stem cells, myeloid population and peripheral T and B cells. Non-activated splenocytes from Ly-6.2 strains including C57BL, SJL, 129, AKR, and others demonstrate higher frequency of D7-positive cells compared to the Ly-6.1 strains such as BALB/c, C3H, NZB and others. Sca-1 is expressed at high levels upon activation regardless of the Ly-6 haplotype. The Ly-6 family is involved in regulation and function of T cell activation. Sca-1 is a major phenotypic marker for mouse hematopoietic progenitor/stem cell subset.