Thermo Scientific™ LanthaScreen™ Tb-anti-LRRK2 [pSer935] Antibody

This assay format provides a convenient tool for the expression of LRRK2-GFP fusion protein in the cell background of the user's choice. The resulting cellular assay can be used to identify LRRK2 and relevant mutant inhibitor.

Product Code	Brand	Quantity
13335554	Thermo Scientific™ A14690	25 μg
13345554	Thermo Scientific™ A14693	100 μg
13355554	Thermo Scientific™ A14694	1 mg

Description

• The LanthaScreen™ Tb-Anti-LRRK2 [pSer935] Antibody allows the investigation of phosphorylation at serine 935 on LRRK2 protein kinase
• When paired with LRRK2 BacMam reagents, users have the freedom to choose the cellular background for their assay, including primary cells
• This enables screening for potential inhibitors of LRRK2 proteins in their natural complexes in a physiologically relevant cell type
• This antibody has been specifically developed and optimized for use in our LanthaScreen™ TR-FRET LRRK2 Cellular Activity Assay Kits
• The antibody, as well as other components of these assay kits, are also available separately
• Can be used by Parkinson's and other disease researchers to perform HTS, cell-based assays to generate inhibition curves (IC50) for their compound libraries
• This will aid drug discovery efforts by reducing the time to results from 4 hrs to typically 1.5 hrs compared to alternative ELISAs
• For research use only
• Not intended for animal or human diagnostic or therapeutic use

Specifications

• For Use With (Equipment): HTS Reader
• Product Line: LanthaScreen
• Shipping Condition: Dry Ice
• Target Modification State: Phospho

• Host Species: Rabbit
• Reactivity: Human
• Classification: Monoclonal

For Research Use Only. Not for use in diagnostic procedures.