Thermo Scientific™ LanthaScreen™ Tb-anti-LRRK2 [pSer935] Antibody

This assay format provides a convenient tool for the expression of LRRK2-GFP fusion protein in the cell background of the user's choice. The resulting cellular assay can be used to identify LRRK2 and relevant mutant inhibitor.

Brand:  Thermo Scientific™ A14693

Product Code. 13345554

Description

• The LanthaScreen™ Tb-Anti-LRRK2 [pSer935] Antibody allows the investigation of phosphorylation at serine 935 on LRRK2 protein kinase
• When paired with LRRK2 BacMam reagents, users have the freedom to choose the cellular background for their assay, including primary cells
• This enables screening for potential inhibitors of LRRK2 proteins in their natural complexes in a physiologically relevant cell type
• This antibody has been specifically developed and optimized for use in our LanthaScreen™ TR-FRET LRRK2 Cellular Activity Assay Kits
• The antibody, as well as other components of these assay kits, are also available separately
• Can be used by Parkinson's and other disease researchers to perform HTS, cell-based assays to generate inhibition curves (IC50) for their compound libraries
• This will aid drug discovery efforts by reducing the time to results from 4 hrs to typically 1.5 hrs compared to alternative ELISAs
• For research use only
• Not intended for animal or human diagnostic or therapeutic use

Specifications

• Classification: Monoclonal
• Gene Accession No.: NP_940980.3
• Quantity: 100 μg
• Content And Storage: 1 tube LanthaScreen™ Tb-anti-LRRK2 [pSer935] Antibody 100 μg, Store at -20 °C
• Host abrv: Rb
• Shipping Condition: Dry Ice
• Target Modification State: Phospho
• Product Line: LanthaScreen

• Conjugate: Tb (Terbium)/Lanthanide Chelates
• Host Species: Rabbit
• Gene ID (Entrez): 120892
• For Use With (Equipment): HTS Reader
• Reactivity: Human
• Reactivity abrv: Hu
• Target Gene: LRRK2

For Research Use Only. Not for use in diagnostic procedures.