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Epredia™ Lab Vision™ XPA Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide
Provide accurate, reproducible results with the Epredia™ XPA Ab-1, Mouse Monoclonal Antibody.
Brand: Epredia™ MS-650-P1ABX
This item is not returnable.
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Description
The XPA (xeroderma pigmentosum group A) protein specifically recognizes the UV-or chemically damaged DNA lesions, and triggers the nucleotide excision repair process. XPA binds to the replication protein A (RPA) or the excision repair cross complementing 1 protein (ERCC1). In the absence of nucleotide excision repair persisting (unrepaired) DNA lesions (adducts) may lead to the accumulation of gene mutations and ultimately to cancer. Xeroderma pigmentosum patients have a > 2000 fold increased risk to develop skin cancer at sun-exposed areas.Host Species: Mouse
Clone: 12F5
Isotype: IgG2a/k
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Recombinant human XPA protein
Molecular Weight: ∽40kDa
Positive Control: Ls174T or MCF-7 cells or human tonsil
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
Note:
USA: RUO; Int'l: RUO
Specifications
| XPA Ab-1 | |
| Monoclonal | |
| 1mg/mL | |
| Mouse | |
| 100 μL | |
| DNA Repair | |
| Human | |
| IgG2a κ |
| Western Blot | |
| 12F5 | |
| Unconjugated | |
| Recombinant human XPA protein | |
| RUO | |
| Primary | |
| Concentrated |
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