Epredia™ Lab Vision™ XPA Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Provide accurate, reproducible results with the Epredia™ XPA Ab-1, Mouse Monoclonal Antibody.

Brand:  Epredia™ MS-650-P0

Product Code. 12621917

Description

The XPA (xeroderma pigmentosum group A) protein specifically recognizes the UV-or chemically damaged DNA lesions, and triggers the nucleotide excision repair process. XPA binds to the replication protein A (RPA) or the excision repair cross complementing 1 protein (ERCC1). In the absence of nucleotide excision repair persisting (unrepaired) DNA lesions (adducts) may lead to the accumulation of gene mutations and ultimately to cancer. Xeroderma pigmentosum patients have a > 2000 fold increased risk to develop skin cancer at sun-exposed areas.

Host Species: Mouse

Clone: 12F5

Isotype: IgG2a/k

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human XPA protein

Molecular Weight: ∽40kDa

Positive Control: Ls174T or MCF-7 cells or human tonsil

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: XPA Ab-1
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Quantity: 100 μL
• Research Discipline: DNA Repair
• Target Species: Human
• Isotype: IgG2a κ

• Applications: Western Blot
• Clone: 12F5
• Conjugate: Unconjugated
• Immunogen: Recombinant human XPA protein
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated