missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. Surfactant Protein B (Precursor) Ab-1 Mouse Monoclonal Antibody, Epredia™
  7. 12662087

Surfactant Protein B (Precursor) Ab-1 Mouse Monoclonal Antibody, Epredia™

Epredia™ Surfactant Protein B (Precursor) Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.

Brand:  Epredia MS-704-R7

 View more versions of this product

Product Code. 12662087

This item is currently unavailable or has been discontinued.
View the product page for possible alternatives.
 View alternative products »

This item is not returnable. View return policy

Description

Description

Pulmonary surfactant is a complex mixture of phospholipids and proteins that is secreted from type II cells in alveoli and reduces the surface tension at the alveolar air-liquid interface, providing alveolar stability necessary for normal ventillation. Four distinct proteins isolated from pulmonary surfactant are termed surfactant proteins A, B, C, and D. SP-A (28-36kDa) and SP-D (43kDa) are collagenous carbohydrate-binding proteins, whereas SP-B (8-9kDa) and SP-C (4kDa) are non-collagenous hydrophobic proteins. SP-B is expressed in pulmonary adenocarcinomas with acinar, papillary, bronchioloalveolar, and solid growth patterns. Squamous cell and large cell carcinomas of the lung and nonpulmonary adenocarcinomas do not express SP-B. ProSP-B is glycosylated in the Golgi apparatus and undergoes carboxy- and amino-terminal proteolysis by a cathepsin D-like protease.

Host Species: Mouse

Clone: SPB01; same as 1-2-A5-9

Isotype: IgG2a/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Recombinant prosurfactant protein B

Molecular Weight: 42-46kDa

Positive Control: Lung adenocarcinoma

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Immunofluorescence

Note:

USA: RUO; Int'l: RUO

TRUSTED_SUSTAINABILITY
Specifications

Specifications

Surfactant Protein B (Precursor) Ab-1
Monoclonal
Prediluted
Mouse
7 mL
Cancer and Tumor Biology
Human, Rat
IgG2a κ
Immunofluorescence, Immunohistochemistry (Paraffin)
SPB01; same as 1-2-A5-9
Unconjugated
Recombinant pro-surfactant protein B
RUO
Primary
Prediluted
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.