Epredia™ Lab Vision™ Mast Cell Tryptase Ab-2 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Epredia™ Mast Cell Tryptase Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.

Brand:  Epredia™ MS-1216-P1

Product Code. 12649296

Description

Mast cells contain a number of preformed chemical mediators such as histamine, chymase, carboxypeptidase and proteolytic tryptase. A substantial quantity of tryptase is estimated to be found in mast cells of skin and lung and suggestes this enzyme plays a major role in mast cell mediated events. In vitro studies indicate tryptase can cleave C3 to form C3a anaphylatoxin, inactivate fibrinogen as a coaguable substrate for thrombin and activate latent collagenase. Human mast cell tryptase has considerable potential as a marker for mast cell activation as well as being a mediator of inflammation.

Host Species: Mouse

Clone: AA1

Isotype: IgG1

Species Reactivity: Human, Monkey, Dog and Cat. Others not known.

Epitope: Not determined

Immunogen: Human mast cell tryptase purified from human lung tissues

Positive Control: Tonsil

Cellular Localization: Cytoplasmic

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Mast Cell Tryptase Ab-2
• Classification: Monoclonal
• Concentration: 50μg/mL
• Host Species: Mouse
• Quantity: 500 μL
• Research Discipline: Enzyme
• Target Species: Canine, Feline, Human, Non-human Primate
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: AA1
• Conjugate: Unconjugated
• Immunogen: Human mast cell tryptase purified from human lung tissues
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated