Epredia™ Lab Vision™ HER-4/c-erbB-4 Rabbit Polyclonal Antibody with BSA and azide

Recommended for Immunohistochemistry (Formalin/paraffin) and Western Blotting, Epredia™ HER-4/c-erbB-4, Rabbit Polyclonal Antibody provides accurate, reproducible results.

Product Code	Brand	Quantity	Form
12603417	Epredia™ RB-9045-P1	500 μL	Concentrated

Description

c-erbB-4 is the fourth member of class I receptor kinase family. HER-4 is most predominantly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain, and cerebellum. Breast tumor cell lines T47-D, MDA-MB-453, BT-474 and H3396 are found to have the highest levels of mRNA, and intermediate levels are seen in MCF-7, MDA-MB-330 and MDA-MB-361. Expression of erbB-4 is low or absent in some breast tumor cell lines such as MDA-MB-231, MDA-MB-157, MDA-MB-468, and SKBR-3.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human and Mouse. Others not tested.

Epitope: C-terminal

Immunogen: A synthetic peptide from C-terminus of human HER-4 protein

Molecular Weight: 185kDa

Positive Control: Breast CA T47D cells

Cellular Localization: Cytoplasmic and membrane

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: HER-4/c-erbB-4
• Classification: Polyclonal
• Host Species: Rabbit
• Research Discipline: EGFR Family
• Immunogen: A synthetic peptide from C-terminus of human c-erbB-4 protein
• Primary or Secondary: Primary

• Applications: Western Blot
• Conjugate: Unconjugated
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG