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Tocris Bioscience™ L-655,708

Product Code. 18044512
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18044512 50 mg 50mg
18015292 10 mg 10mg
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Product Code. 18044512 Supplier Tocris Bioscience™ Supplier No. 1327/50

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599.20 GBP valid until 2026-03-31
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Description

Benzodiazepine inverse agonist; selective for α5-containing GABAA receptors

Potent, selective inverse agonist for the benzodiazepine site of GABAA receptors containing the α5 subunit (Ki = 0.45 nM). Displays 50-100-fold selectivity over GABAA receptors containing α1, α2, α3 or α6 subunits in combination with β3 and γ2. Enhances LTP in a mouse hippocampal slice model and increases spatial learning, without displaying proconvulsant activity.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 130477-52-0
Molecular Formula C18H19N3O4

Specifications

Quantity 50 mg
Formula Weight 341.37
Purity >99%
Molecular Weight (g/mol) 341.367
Chemical Name or Material L-655, 708
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