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Tocris Bioscience™ L-655,708
Description
Potent, selective inverse agonist for the benzodiazepine site of GABAA receptors containing the α5 subunit (Ki = 0.45 nM). Displays 50-100-fold selectivity over GABAA receptors containing α1, α2, α3 or α6 subunits in combination with β3 and γ2. Enhances LTP in a mouse hippocampal slice model and increases spatial learning, without displaying proconvulsant activity.
Specifications
Specifications
| Quantity | 10 mg |
| Formula Weight | 341.37 |
| Purity | >99% |
| Molecular Weight (g/mol) | 341.367 |
| Chemical Name or Material | L-655, 708 |
Product Title
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