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Invitrogen™ KIT [Y823D] Recombinant Human Protein
KIT (c-KIT) Y823D encodes the ligand-binding chain (alpha) of the gamma interferon receptor which is a heterodimer of IFNGR1 and IFNGR2. Recombinant human KIT Y823D (544-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Brand: Invitrogen™ PV6322
Code : NEW
Additional Details : Weight : 0.01000kg
Description
KIT Y823D is a regulator of hematopoietic stem cells during homeostasis and under conditions of infectious stress. A genetic variation in KIT Y823D is associated with susceptibility to Helicobacter pylori infection. In addition, defects in KIT Y823D are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. KIT Y823D is also associated with the clinical outcome of HBV infection in Chinese adults.
- Validated in LanthaScreen™ Kinase Binding Assay
- Protocols available for simple use and optimized performance
- Multiple pack sizes available for convenient use
Specifications
Enzyme and Protein Activity Assay, Industrial and Applied Science, Kinase Assay, Kinase Biology, Kinase Proteins and Expression Reagents, Pharma and Biopharma, Protein Assays and Analysis, Protein Biology, Target and Lead Identification and Validation | |
75.2kDa | |
Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. | |
aa 544-end | |
Recombinant |
50mM Tris-HCl pH 7.5, 150mM NaCl, 0.25mM DTT, 10mM glutathione, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol | |
10μg | |
PBT, SCFR, CD119 | |
Human | |
GST Tag |