Invitrogen™ KIT [Y823D] Recombinant Human Protein

KIT (c-KIT) Y823D encodes the ligand-binding chain (alpha) of the gamma interferon receptor which is a heterodimer of IFNGR1 and IFNGR2. Recombinant human KIT Y823D (544-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Product Code	Brand	Quantity
15448963	Invitrogen™ PV6322	10μg
15458963	Invitrogen™ PV6323	100μg
15468963	Invitrogen™ PV6324	1mg

Description

KIT Y823D is a regulator of hematopoietic stem cells during homeostasis and under conditions of infectious stress. A genetic variation in KIT Y823D is associated with susceptibility to Helicobacter pylori infection. In addition, defects in KIT Y823D are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. KIT Y823D is also associated with the clinical outcome of HBV infection in Chinese adults.

• Validated in LanthaScreen™ Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Specifications

• For Use With (Application): Enzyme and Protein Activity Assay, Industrial and Applied Science, Kinase Assay, Kinase Biology, Kinase Proteins and Expression Reagents, Pharma and Biopharma, Protein Assays and Analysis, Protein Biology, Target and Lead Identification and Validation
• Molecular Weight (g/mol): 75.2kDa
• Gene Alias: PBT, SCFR, CD119
• Species: Human
• Protein Tag: GST Tag

• Formulation: 50mM Tris-HCl pH 7.5, 150mM NaCl, 0.25mM DTT, 10mM glutathione, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol
• Storage Requirements: Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.
• Protein Length: aa 544-end
• Recombinant: Recombinant