Invitrogen™ KISS1 Monoclonal Antibody (C1), Invitrogen™

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
17654136	Invitrogen™ MA543681	20 μL
17644136	Invitrogen™ MA543680	100 μL

Description

This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH neurons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues.

Specifications

• Antigen: KISS1
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Alias: 0610012C01Rik; Eseptin; HH13; KISS1; KiSS-1; KiSS-1 metastasis-suppressor; Kiss1 metastasis-suppressor; Kiss1 variant E1a-E2b-E3; Kiss1 variant E1b-E2a-E3; Kiss1 variant E1b-E2b-E3; kisspeptin; Kisspeptin-1; Kisspeptin-10; Kisspeptin-13; Kisspeptin-14; Kisspeptin-52; Kisspeptin-54; malignant melanoma metastasis-suppressor; metastasis-suppressor KiSS-1; metastatin; metastin; Metastin45-54; MLL septin-like fusion; PP5098; prepro-kisspeptin
• Gene Symbols: KISS1
• Isotype: IgG1 κ
• Purification Method: Protein A/G
• Product Type: Antibody

• Clone: C1
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: Q15726
• Gene ID (Entrez): 3814
• Immunogen: Glu20-Gly138 (Accession Q15726), with N-terminal His Tag.
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Gene: KISS1