CellSensor™ ISRE-bla HEK293T Cell Line

CellSensor™ ISRE-bla HEK293T Cell Line is responsive to interferon alpha and can be used to probe the JAK/STAT signaling pathway.

Brand:  CellSensor™ K1655

Product Code. 10563084

Description

• Interferon cell signaling is a critical pathway involved in viral defense and autoimmune disease.
• The CellSensor™ ISRE-bla HEK 293T cell line contains the β-lactamase reporter gene under the control of the interferon stimulated response element (ISRE).
• This cell line was engineered by transduction of the ISRE-bla construct into HEK 293T cells by lentivirus.
• Flow cytometry was then used to isolate a pool of clones responsive to interferon alpha a stimulation.
• A dose response curve for this assay against interferon alpha is available in the validation packet.

Specifications

• Content And Storage: Store in liquid nitrogen immediately upon receipt, or thaw for immediate use
• For Use With (Application): Cytokines, Signaling Pathway
• Quantity: 1 Vial
• Type: Dividing Cells