Isopropylmagnesium chloride - LiCl complex, 1M in MeTHF

Product Code. 15449205

Brand: Thermo Scientific Alfa Aesar H51156.AE

Description

CAS: 807329-97-1 | C3H7Cl2LiMg | 145.23 g/mol

Isopropylmagnesium chloride is used in the regioselective functionalization of trisubstituted pyridines, electrophilic amination for preparation of amines and functionalization of cyclopentene derivatives. It is involved in the preparation of 2,3-functionalized furans, benzofurans, and thiophenes. Further, it is used in benzylic Grignards via sulfur-magnesium exchange.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Isopropylmagnesium chloride is used in the regioselective functionalization of trisubstituted pyridines, electrophilic amination for preparation of amines and functionalization of cyclopentene derivatives. It is involved in the preparation of 2,3-functionalized furans, benzofurans, and thiophenes. Further, it is used in benzylic Grignards via sulfur-magnesium exchange.

Solubility
Miscible with ethers and amines.

Notes
Air and moisture sensitive. Incompatible with oxidizing agents and water.

Specifications

Chemical Identifiers

• CAS: 807329-97-1
• Molecular Formula: C3H7Cl2LiMg
• Molecular Weight (g/mol): 145.23
• MDL Number: MFCD07784514
• InChI Key: CWTUREABAILGIK-UHFFFAOYSA-L
• Synonym: turbo grignard, iprmgcl licl, i-prmgcl licl, i-prmgcl.licl, isopropylmagnesiumchloride licl, isopropylmagnesium chloride licl, isopropyl magnesium chloride licl, cwtureabailgik-uhfffaoysa-l, isopropylmagnesium lithium chloride, isopropyl magnesium chloride li-cl
• IUPAC Name: lithium(1+) chloro(propan-2-yl)magnesium chloride
• SMILES: [Li+].[Cl-].CC(C)[Mg]Cl

• Density: 0.951
• Flash Point: −17°C (1.4°F)
• Linear Formula: (CH₃)₂CHMgCl·LiCl
• Quantity: 100 mL
• UN Number: UN3399
• Sensitivity: Air and moisture sensitive
• Solubility Information: Miscible with ethers and amines.
• Formula Weight: 145.24
• Concentration or Composition (by Analyte or Components): 1M in MeTHF
• Chemical Name or Material: Isopropylmagnesium chloride - LiCl complex

Safety and Handling

Product Identifier

• Isopropylmagnesium chloride - LiCl complex, 1M in MeTHF

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 1
• Flammable liquid Category 2
• Skin corrosion/irritation Category 1 B
• Substance which\, in contact with water\, emits flammable gases Category 1

Hazard Statement

• H225-Highly flammable liquid and vapour.
• H260-In contact with water releases flammable gases which may ignite spontaneously.
• H302-Harmful if swallowed.
• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.
• EUH014-Reacts violently with water.
• EUH019-May form explosive peroxides.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P231+P232-Handle under inert gas. Protect from moisture.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.
• P335+P334-Brush off loose particles from skin Immerse in cool water/wrap in wet bandages.

Supplemental information

• MIXTURE LIST-Contains : 2-Methyltetrahydrofuran, Isopropylmagnesium chloride

SDS

RUO – Research Use Only