Integrin beta-3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16898384	Proteintech 18309-1-AP-20UL	20 μL
16888384	Proteintech 18309-1-AP-150UL	150 μL

Description

ITGB3 is involved in Glanzmann thrombasthenia (GT), a common inherited disease of platelet aggregation. It is characterized by mucocutaneous bleeding of mild-to-moderate severity. GT has been classified clinically into types I and II. In type I, platelets show absence of the glycoprotein IIb-IIIa complexes at their surface and lack fibrinogen and clot retraction capability. In type II, the platelets express the GPIIb-IIIa complex at reduced levels, have detectable amounts of fibrinogen, and have low or moderate clot retraction capability. The disease is caused by mutations affecting the gene represented in this entry.

Specifications

• Antigen: Integrin beta-3
• Applications: Western Blot, Immunoprecipitation
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Mouse, Rat, Human
• Gene Accession No.: O54890, P05106
• Gene ID (Entrez): 16416, 29302, 3690
• Immunogen: Peptide
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: ITGB3

• Concentration: 0.27 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: CD61, GP3A, GPIIIa, Integrin beta 3, Integrin beta-3, ITGB3
• Gene Symbols: ITGB3
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody