Invitrogen™ ICOS (CD278) Recombinant Rabbit Monoclonal Antibody (8P2G3)

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
30282730	Invitrogen™ MA558129	20 μL
30284537	Invitrogen™ MA558130	100 μL

Description

Immunogen sequence: EINGSADHRM FSFHNGGVQI SCKYPETVQQ LKMRLFRERE VLCELTKTKG SGNAVSIKNP MLCLYHLSNN SVSFFLNNPD SSQGSYYFCS LSIFDPPPFQ ERNLSGGYLH IYESQLCCQL KL.

ICOS (CD278) encodes a protein that is a member of the CD28 and CTLA-4 cell-surface receptor family. It functions as a homodimer and has a crucial role in cell-cell signaling, immune responses, and the regulation of cell proliferation. ICOS has been linked to various disorders, including Immunodeficiency, Common Variable, 1 and Common Variable Immunodeficiency.

Specifications

• Antigen: ICOS (CD278)
• Concentration: 1.63 mg/mL
• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: Q9R1T7, Q9WVS0
• Gene ID (Entrez): 54167, 64545
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-142 of mouse ICOS/CD278 (NP_059508.2).
• Product Type: Antibody

• Clone: 8P2G3
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Mouse, Rat
• Gene: ICOS
• Gene Alias: Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
• Gene Symbols: ICOS
• Primary or Secondary: Primary
• Purification Method: Protein A