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Molecular Probes™ IAEDANS (1,5-IAEDANS, 5-((((2-Iodoacetyl)amino)ethyl)amino)Naphthalene-1-Sulfonic Acid)
Description
The fluorescence of the thiol-reactive IAEDANS is quite dependent upon environment. Its conjugates frequently respond to ligand binding by undergoing spectral shifts and changes in fluorescence intensity that are determined by the degree of aqueous solvation. Advantages of this reagent include high water solubility above pH 4 and a relatively long fluorescence lifetime (10-15 nanoseconds), making the conjugates useful for fluorescence polarization and rotational studies. In addition, because it has a large Stokes shift and an emission that overlaps with the absorption of fluorescein, Alexa Fluor™ 488, Oregon Green™ dyes and BODIPY™ FL dyes, IAEDANS is an excellent reagent for fluorescence resonance energy transfer (FRET) measurements.
Specifications
Specifications
| Quantity | 100 mg |
| Product Type | IAEDANS |
| Content And Storage | Store in freezer (-5 to -30°C) and protect from light. |
| Chemical Reactivity | Thiol |
| Shipping Condition | Room Temperature |
| Reactive Moiety | Alkyl Halide, Iodoacetamide |
| Label or Dye | Naphthalene |
| Label Type | Classic Dyes |
For Research Use Only. Not for use in diagnostic procedures.
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