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Invitrogen™ VWF Human ELISA Kit
Sandwich ELISA Kit
Brand: Invitrogen™ EHVWF
Code : NEW
Additional Details : Weight : 0.33000kg
Description
Factor VIII related antigen or von Willebrand factor is a multimeric glycoprotein. It has functional binding domains to platelet glycoprotein Ib, glycoprotein IIb/IIIa, collagen and heparin. von Willebrand factor is synthesized by endothelial cells and stored in the Weibel-Palade granules. It mediates platelet adhesion to injured vessel walls and serves as a carrier and stabilizer for coagulation factor VIII. von Willebrand factor is one of the most useful markers to identify endothelial (or megakaryocytic) lineage of neoplasms. As not all endothelial cells synthesize/ store) this molecule, about 30% of tumors of vascular origin fail to stain for factor VIII related antigen, regardless of whether they are benign or malignant. Staining for factor VIII related antigen has also been used to measure angiogenesis, an indicator of tumor recurrence.Specifications
| P04275 | |
| 0.4ng/mL to 120ng/mL | |
| ELISA, Protein Assays, Protein Biology, Cancer Biology, Immunology, Neuroscience, Neurobiology, Protein Detection, Protein Analysis | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| RUO | |
| 100 μL per sample after dilution | |
| This ELISA antibody pair detects human vWF. Other species not determined. | |
| 96 assays | |
| 4 hr. 45 min. | |
| Solid-phase sandwich ELISA | |
| Angiogenesis | |
| F8VWF, VWD | |
| <10% | |
| Human | |
| HRP |
| 0.123-30 ng/mL | |
| Biotin | |
| 7450 | |
| ELISA Kit | |
| 0.13 ng/mL | |
| Plasma, 2 μL|Serum, 2 μL|Supernatant, 100 μL | |
| 2°C to 8°C | |
| 1 hr. 20 min. | |
| Human | |
| Other Proteins | |
| F8VWF,VWD | |
| <12% | |
| 96 Tests | |
| Supernatant | |
| Colorimetric Microplate Reader |