HSPB8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16854404	Proteintech 15287-1-AP-20UL	20 μL
16844404	Proteintech 15287-1-AP-150UL	150 μL

Description

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Specifications

• Antigen: HSPB8
• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Rat, Mouse, Human
• Gene Accession No.: Q9EPX0, Q9JK92, Q9UJY1
• Gene ID (Entrez): 113906, 26353, 80888
• Immunogen: HSPB8 Fusion Protein Ag7456
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: HSPB8

• Concentration: 0.17 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: Alpha crystallin C chain, CMT2L, CRYAC, DHMN2, E2 induced gene 1 protein, E2IG1, H11, heat shock 22kDa protein 8, Heat shock protein beta 8, HMN2, HMN2A, HSP22, HSPB8, Protein kinase H11
• Gene Symbols: Hspb8
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody