HSPB8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 15287-1-AP-20UL

Product Code. 16854404

Description

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Specifications

• Antigen: HSPB8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HSPB8
• Gene Alias: Alpha crystallin C chain, CMT2L, CRYAC, DHMN2, E2 induced gene 1 protein, E2IG1, H11, heat shock 22kDa protein 8, Heat shock protein beta 8, HMN2, HMN2A, HSP22, HSPB8, Protein kinase H11
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 113906, 26353, 80888
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, Western Blot
• Concentration: 0.17 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9EPX0, Q9JK92, Q9UJY1
• Gene Symbols: Hspb8
• Immunogen: HSPB8 Fusion Protein Ag7456
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Rat, Mouse, Human
• Product Type: Antibody
• Isotype: IgG