Invitrogen™ HNF6 Recombinant Rabbit Monoclonal Antibody (7L3O1)

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
30282706	Invitrogen™ MA558123	20 μL
30282712	Invitrogen™ MA558124	100 μL

Description

Immunogen sequence: PYHKDVAGMG QSLSPLSSSG LGSIHNSQQG LPHYAHPGAA MPTDKMLTPN GFEAHHPAML GRHGEQHLTP TSAGMVPING LPPHHPHAHL NAQGHGQLLG TAREPNPSVT GAQVSNGSNS GQMEEI.

Hepatocyte nuclear factor 6 is a CUT homeobox family protein which is a transcription factor and contains a CUT DNA-binding domain and a homeobox DNA-binding domain. It is an upstream regulator of several genes involved in the pathogenesis of maturity-onset diabetes of the young. HNF6 is a ligand of the FOXM1 transcription factor network. HNF6, along with HNF4, controls gene expression in the liver. The expression levels of HNF6 and HNF4 rise steadily during development and that up- or down regulation of HNF6 and HNF4 expression generate premature or delayed expression of the g6pc gene.

Specifications

• Antigen: HNF6
• Concentration: 2.29 mg/mL
• Applications: ELISA, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: O08755, P70512
• Gene ID (Entrez): 15379, 25231
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 167-292 of human HNF-6/ONECUT1 (NP_004489.1).
• Product Type: Antibody

• Clone: 7L3O1
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Mouse, Rat
• Gene: ONECUT1
• Gene Alias: D9Ertd423e; hepatic nuclear factor 6; hepatocyte nuclear factor 6; hepatocyte nuclear factor 6 alpha; hepatocyte nuclear factor 6, alpha; Hfh12; HNF-3/forkhead homolog 12; hnf6; HNF-6; Hnf6a; HNF-6a; Hnf6b; Oc1; OC-1; One cut domain family member 1; one cut domain, family member 1; one cut domain, family member 1, like; one cut homeobox 1; Onecut1; onecut-1 isoform a; onecut-1 isoform b; onecut1 protein; onecut1l; transcription factor; hepatocyte nuclear factor 6; hnf-6; zgc:65904; zgc:77450
• Gene Symbols: ONECUT1
• Primary or Secondary: Primary
• Purification Method: Protein A