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  6. Cytiva™ HiTrap™ Chromatography Columns with MabSelect™ VL Protein L Resin

Cytiva™ HiTrap™ Chromatography Columns with MabSelect™ VL Protein L Resin

Product Code. p-7250485 Shop All Cytiva Products
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Quantity:
1 x 1 mL
1 x 5 mL
5 x 1 mL
5 x 5 mL
Bed Volume:
1 mL
5 mL
Diameter (Metric) Inner:
7 mm
16 mm
Flow Rate:
<20 mL/min.
<4 mL/min.
Unit Size:
25mL
5mL
Each
Product Code. Quantity Bed Volume Diameter (Metric) Inner Flow Rate unitSize
17841532 1 x 1 mL 1 mL 7 mm <4 mL/min. Each
17847774 5 x 1 mL 1 mL 7 mm <4 mL/min. 5mL
17897764 1 x 5 mL 5 mL 16 mm <20 mL/min. 5mL
17817774 5 x 5 mL 5 mL 16 mm <20 mL/min. 25mL
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Product Code. 17841532

Brand: Cytiva™ 17542051

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This item is not returnable. View return policy

Description

Protein L affinity chromatography columns for capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain.

  • Redesigned protein L ligand captures antibody Fabs, bispecifics, and other variants containing a kappa light chain with high binding capacity and improved alkaline stability
  • High dynamic binding capacity for efficient capture of target molecules
  • Stable when cleaned with 0.1 M NaOH, reducing risk for bioburden incidents
  • Provides good resolution for product-related impurities in the capture of bispecific antibodies

As the diversity of antibody variants increases, so does the need for chromatography resins that can capture and purify these variants. As an alternative to protein A, protein L can be used to capture antibody Fabs, bispecific antibodies, and other molecules containing kappa variants of the variable light (VL) chain. Protein L binds human kappa light chain subtypes 1, 3, and 4 and mouse kappa light chain subtype 1.

TRUSTED_SUSTAINABILITY

Specifications

Bed Volume 1 mL
Diameter (English) Inner 0.3 in.
Diameter (Metric) Inner 7 mm
Quantity 1 x 1 mL
Height (English) 1 in.
Height (Metric) 25 mm
Flow Rate <4 mL/min.
Max. Pressure 5 bar
Column Type Affinity Column
For Use With (Application) Antibody Affinity Chromatography

Safety and Handling

compliance-icons
Product Identifier
  • HiTrap MabSelect VL, 1 x 1 ml
 Signal Word
  • Warning
 Hazard Category
  • Flammable liquid Category 3
 Hazard Statement
  • H226-Flammable liquid and vapour.
 Precautionary Statement
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Supplemental information
  • MIXTURE LIST-Contains : ethanol
Product Title
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