Cytiva™ HiTrap™ Chromatography Columns with MabSelect™ VL Protein L Resin

Product Code.	Quantity	Bed Volume	Diameter (Metric) Inner	Flow Rate	unitSize
17841532	1 x 1 mL	1 mL	7 mm	<4 mL/min.	Each
17847774	5 x 1 mL	1 mL	7 mm	<4 mL/min.	5mL
17897764	1 x 5 mL	5 mL	16 mm	<20 mL/min.	5mL
17817774	5 x 5 mL	5 mL	16 mm	<20 mL/min.	25mL

Product Code. 17841532 Supplier Cytiva™ Supplier No. 17542051

Beschreibung

Protein L affinity chromatography columns for capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain.

• Redesigned protein L ligand captures antibody Fabs, bispecifics, and other variants containing a kappa light chain with high binding capacity and improved alkaline stability
• High dynamic binding capacity for efficient capture of target molecules
• Stable when cleaned with 0.1 M NaOH, reducing risk for bioburden incidents
• Provides good resolution for product-related impurities in the capture of bispecific antibodies

As the diversity of antibody variants increases, so does the need for chromatography resins that can capture and purify these variants. As an alternative to protein A, protein L can be used to capture antibody Fabs, bispecific antibodies, and other molecules containing kappa variants of the variable light (VL) chain. Protein L binds human kappa light chain subtypes 1, 3, and 4 and mouse kappa light chain subtype 1.

Spezifikation

• Bed Volume: 1 mL
• Diameter (English) Inner: 0.3 in.
• Diameter (Metric) Inner: 7 mm
• Quantity: 1 x 1 mL
• Height (English): 1 in.
• Height (Metric): 25 mm
• Flow Rate: <4 mL/min.
• Max. Pressure: 5 bar
• Column Type: Affinity Column
• For Use With (Application): Antibody Affinity Chromatography

Sicherheit und Handhabung

Produktidentifikator

• HiTrap MabSelect VL, 1 x 1 ml

Signalwort

• Warning

Gefahrenkategorie

• Flammable liquid Category 3

Gefahrenhinweis

• H226-Flammable liquid and vapour.

Sicherheitshinweis

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Ergänzende Informationen

• MIXTURE LIST-Contain: ethanol