Cytiva HiScreen™ Capto™ adhere Multimodal Prepacked Column

Product Code. 10201180

Brand: Cytiva 28926981

Description

For intermediate purification and polishing of monoclonal antibodies after the protein A capture step

• Strong multimodal anion exchanger with N-benzyl-n-methyl ethanolamine ligand
• Offers alternative selectivity compared to traditional anion exchangers
• In flowthrough mode, removal of leached protein A, aggregates, host cell proteins, nucleic acids and viruses from MAbs is performed
• Antibodies pass directly through the column while the contaminants remain bound
• Highly cross-linked agarose matrix
• Ready-to-use columns for convenient process development optimization
• Bed height of 10cm is designed to allow method optimization and parameter screening
• Easily connected in series to achieve 20cm bed height

Specifications

• Buffer: 1M Acetic Acid, 1M NaOH
• Product Type: HiScreen Capto adhere column
• Bed Volume: 4.7mL
• Diameter (English) Inner: 0.3 in.
• Diameter (Metric) Inner: 7.7mm
• Quantity: 1 x 4.7mL
• Height (English): 3.93 in.
• Height (Metric): 100mm
• Flow Rate: <600cm/hr.
• Material: Polypropylene
• Ligand Type: N-benzyl-n-methyl Ethanolamine
• Max. Pressure: 3 bar
• pH Range: 3 to 12
• Particle Size: 75μm
• Support Type: Highly Cross-linked Agarose
• Content And Storage: 4° to 30°C
• Column Type: Multimodal Column
• For Use With (Application): Optimization and parameter screening

Safety and Handling

Product Identifier

• HiScreen Capto adhere

Signal Word

• Warning

Hazard Category

• Flammable liquid Category 3

Hazard Statement

• H226-Flammable liquid and vapour.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P241-Use explosion-proof electrical/ventilating/lighting/ equipment.
• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P405-Store locked up.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information

• MIXTURE LIST-Contains : ethanol
• UNKNOWN ACUTE-16.5 per cent of the mixture consists of component(s) of unknown acute toxicity.