HEXA Mouse anti-Human, Clone: 3A4F2, Proteintech

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
16847445	Proteintech 60337-1-IG-20UL	20 μL
16837445	Proteintech 60337-1-IG-150UL	150 μL

Description

This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).

Specifications

• Antigen: HEXA
• Concentration: 1.86 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: HEXA, Hexosaminidase subunit A, TSD
• Gene Symbols: HEXA
• Isotype: IgG2b
• Purification Method: Protein A
• Product Type: Antibody

• Clone: 3A4F2
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: P06865
• Gene ID (Entrez): 3073
• Immunogen: HEXA Fusion Protein Ag1854
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: HEXA