HEXA Mouse anti-Human, Clone: 3A4F2, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 60337-1-IG-150UL

Product Code. 16837445

Description

This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).

Specifications

• Antigen: HEXA
• Classification: Monoclonal
• Concentration: 1.86 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P06865
• Gene Symbols: HEXA
• Immunogen: HEXA Fusion Protein Ag1854
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot
• Clone: 3A4F2
• Conjugate: Unconjugated
• Gene: HEXA
• Gene Alias: HEXA, Hexosaminidase subunit A, TSD
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3073
• Content And Storage: -20°C
• Form: Liquid