HER-2/c-erbB-2/neu Ab-16 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ HER-2/c-erbB-2/neu Ab-16, Mouse Monoclonal Antibody.

Brand:  Epredia MS-600-P1A

Product Code. 12601737

Description

c-erbB-2 is a receptor tyrosine kinase of the c-erbB family. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein

Host Species: Mouse

Clone: L26

Isotype: IgG1/κ

Species Reactivity: Human. Others not tested.

Epitope: Involved in the formation of heterodimers

Immunogen: Extracellular domain of recombinant human HER-2/c-erbB-2 oncoprotein

Molecular Weight: 185kDa

Positive Control: SKBR-3 cells

Cellular Localization: Membrane

Recommended for:

• Immunohistochemistry (Not suitable)
• Western Blotting (Not suitable)
• Immunoprecipitation (Native only)
• Inhibits Binding of EGF (∽70%), NDF (∽40%)
• Reduces Affinity of EGF (3-fold) and NDF (2-fold)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: HER-2/c-erbB-2/neu Ab-16
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Quantity: 500 μL
• Research Discipline: EGFR Family
• Target Species: Human
• Isotype: IgG2a κ

• Applications: Immunoprecipitation
• Clone: L26
• Conjugate: Unconjugated
• Immunogen: Extracellular domain of recombinant human c-erbB-2/HER-2 oncoprotein
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated