GNE Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16883615	Proteintech 25079-1-AP-20UL	20 μL
16873615	Proteintech 25079-1-AP-150UL	150 μL

Description

GNE is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of maligt cells.

Specifications

• Antigen: GNE
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: Q9Y223
• Gene ID (Entrez): 10020
• Immunogen: GNE Fusion Protein Ag18689
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: GNE

• Concentration: 0.39 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: DMRV, GLCNE, GNE, IBM2, ManAc kinase, NM, Uae1, UDP GlcNAc 2 epimerase
• Gene Symbols: GNE
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody