GFI1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16812734	Proteintech 14198-1-AP-20UL	20 μL
16802734	Proteintech 14198-1-AP-150UL	150 μL

Description

GFI1 is a nuclear zinc finger (ZF) transcriptional repressor that plays an important role in hematopoiesis and inner ear development, and has been implicated in lymphomagenesis. The Gfi1 protein expression is regulated by the ubiquitin-proteasome system. It is reported that ubiquitin ligase Triad1 interacts with the DNA-binding domain of Gfi-1. Gfi-1 represses transcription by directly binding to the consensus DNA sequence in the promoters of its target genes. Deficiency of Gfi-1 causes neutropenia and an accumulation of granulomonocytic precursor cells that is reminiscent of a myelodysplastic syndrome in mice.

Specifications

• Antigen: GFI1
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Rat, Human, Mouse
• Gene Accession No.: P70338, Q07120, Q99684
• Gene ID (Entrez): 14581, 24388, 2672
• Immunogen: GFI1 Fusion Protein Ag5401
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: GFI1

• Concentration: 0.14 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: GFI 1, GFI1, Zinc finger protein 163, Zinc finger protein Gfi 1, ZNF163
• Gene Symbols: Gfi1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody