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  6. GFI1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

GFI1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16802734 Shop All Proteintech Products
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150 μL
Unit Size:
150µL
20µL
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16802734 150 μL 150µL
16812734 20 μL 20µL
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Product Code. 16802734 Supplier Proteintech Supplier No. 141981AP150UL

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Description

Rabbit Polyclonal Antibody

GFI1 is a nuclear zinc finger (ZF) transcriptional repressor that plays an important role in hematopoiesis and inner ear development, and has been implicated in lymphomagenesis. The Gfi1 protein expression is regulated by the ubiquitin-proteasome system. It is reported that ubiquitin ligase Triad1 interacts with the DNA-binding domain of Gfi-1. Gfi-1 represses transcription by directly binding to the consensus DNA sequence in the promoters of its target genes. Deficiency of Gfi-1 causes neutropenia and an accumulation of granulomonocytic precursor cells that is reminiscent of a myelodysplastic syndrome in mice.

Specifications

Antigen GFI1
Applications Western Blot
Classification Polyclonal
Concentration 0.14 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene GFI1
Gene Accession No. P70338, Q07120, Q99684
Gene Alias GFI 1, GFI1, Zinc finger protein 163, Zinc finger protein Gfi 1, ZNF163
Gene Symbols Gfi1
Host Species Rabbit
Immunogen GFI1 Fusion Protein Ag5401
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14581, 24388, 2672
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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