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Thermo Scientific™ GeneBLAzer™ VPAC1-CRE-bla CHO-K1 Cells
Beschreibung
CellSensor™ CRE-bla CHO-K1 cells (Cat. no. K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.
The GeneBLAzer™ VPAC1-CRE-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of VIP. In addition, GeneBLAzer™ VPAC1-CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
VPAC1 has been implicated in a wide range of disorders, including Parkinson's disease, septic shock, rheumatoid arthritis, multiple sclerosis, Crohn's disease, and autoimmune diabetes. VPAC1-mediated signaling has also been shown to play a role in HIV infection.
Spezifikation
Spezifikation
| Accession Number | NM_004624 |
| Assay Entry | Cell-based beta lactamase reporter gene |
| Cell State | Dividing Cells |
| Content And Storage | Contents: K1705 GeneBLAzer™ VPAC1-CRE-bla CHO-K1 cells (LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol). Includes: • GeneBLAzer™ VPAC1-CRE-bla CHO-K1 cells • GeneBLAzer™ VPAC1-CRE-bla CHO-K1 Assay Protocol • Certificate of Analysis Storage: The GeneBLAzer™ VPAC1-CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt. |
| Detection Method | Fluorescence |
| For Use With (Application) | FRET |
| Gene Symbol | VPAC1 |
| Population Status | Single Cell Clone Origin |
| Product Line | GeneBLAzer |
| Quantity | 2 x 106 Cells |
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For Research Use Only. Not for use in diagnostic procedures.
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