FOS Mouse anti-Human, Mouse, Clone: 1G2C5, Proteintech

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
16868605	Proteintech 66590-1-IG-20UL	20 μL
16858605	Proteintech 66590-1-IG-150UL	150 μL

Description

FBJ murine osteosarcoma viral oncogene homolog is commonly known as Cellular protooncogene Fos (c-Fos). It belongs to the fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14. c-Fos heterodimerizes with c-Jun to form the Activator Protein -1 (AP-1) transcription factor which regulates transcription of several genes that play an important role in cellular signal transduction, cell proliferation and differentiation. c-Fos has been shown to be phosphorylated by various stimuli including growth factors and insulin at atleast seven different sites. The best known upstream kinase for phosphorylation at Threonine 232 is ERK MAPK which regulates localization of c-Fos to the nucleus and is thus important for c-Fos induced transcriptional activity.

Specifications

• Antigen: FOS
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: AP 1, C FOS, Cellular oncogene fos, FOS, G0S7, Proto oncogene c Fos
• Gene Symbols: FOS
• Isotype: IgG1
• Purification Method: Protein G
• Product Type: Antibody

• Clone: 1G2C5
• Applications: Western Blot, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human, Mouse
• Gene Accession No.: P01100, P01101
• Gene ID (Entrez): 14281, 2353
• Immunogen: FOS Fusion Protein Ag24340
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: FOS