Forskolin, 98+%, Thermo Scientific™

Forskolin, CAS # 66575-29-9, is a diterpenoid compound isolated from Indian Coleus that acts as a strong activator of the adenylate cyclase system.

Brand:  Thermo Scientific Alfa Aesar J63292.MF

Product Code. 15445559

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description

• Forskolin is a diterpenoid and cyclic ketone, found naturally as a plant metabolite

• It is a protein kinase A agonist and a cyclic ketone • Forskolin is an antihypertensive and muscle relaxant; it can also promote the release of pituitary hormones and prevent platelet aggregation

Application

• Forskolin assists in neuron differentiation in vitro

• Useful for studies of cell metabolism and development; there is some evidence of its usefulness in the study of glaucoma

• It is intended for cell culture and biochemistry applications

Chemical Identifiers

• CAS: 66575-29-9
• Molecular Weight (g/mol): 410.507
• InChI Key: OHCQJHSOBUTRHG-KGGHGJDLSA-N
• PubChem CID: 47936
• IUPAC Name: [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate

• Molecular Formula: C22H34O7
• MDL Number: MFCD00082317
• Synonym: forskolin, colforsin, coleonol, colforsina, colforsine, colforsinum, boforsin, colforsine french, colforsinum latin, colforsina spanish
• ChEBI: CHEBI:42471
• SMILES: CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O

Specifications

• CAS: 66575-29-9
• MDL Number: MFCD00082317
• Beilstein: 1692716
• Synonym: forskolin, colforsin, coleonol, colforsina, colforsine, colforsinum, boforsin, colforsine french, colforsinum latin, colforsina spanish
• InChI Key: OHCQJHSOBUTRHG-KGGHGJDLSA-N
• IUPAC Name: [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate
• PubChem CID: 47936
• Formula Weight: 410.51
• Chemical Name or Material: Forskolin

• Molecular Formula: C22H34O7
• Quantity: 50mg
• Merck Index: 14,2476
• Solubility Information: Soluble in ethanol,dimethylsulfoxide and chloroform; Insolule in water.
• SMILES: CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O
• Molecular Weight (g/mol): 410.507
• ChEBI: CHEBI:42471
• Percent Purity: ≥98%