Fibrinopeptide B, Rabbit anti-Human, Clone: 800000, Novus Biologicals™

Rabbit Monoclonal Antibody

Product Code	Brand	Quantity
18320550	Novus Biologicals NBP2-81111-0.025MG	0.025 mg
18300550	Novus Biologicals NBP2-81111-0.2MG	0.2 mg

Description

Fibrin beta-chain Monoclonal specifically detects Fibrin beta-chain in Human samples. It is validated for Flow Cytometry, ELISA, In vivo assay.

Specifications

• Antigen: Fibrinopeptide B
• Concentration: 1 mg/mL
• Applications: ELISA
• Conjugate: Unconjugated
• Host Species: Rabbit
• Research Discipline: Cell Cycle and Replication
• Formulation: PBS
• Gene ID (Entrez): 2244
• Immunogen: 8E5 was prepared fusing Sp2/o myeloma cells with spleen cells derived from female BALB/c mice immunized with a synthetic beta-fibrin peptide seqeunce GHRPLDKC conjugated to MB-KLH (maleimidobenzoylated keyhole limpet hemocyanin).
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Clone: 800000
• Dilution: ELISA, In vivo assay
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human
• Gene Alias: fibrinogen beta chain, fibrinogen, B beta polypeptide, MGC104327, MGC120405
• Gene Symbols: FGB
• Isotype: IgG κ
• Purification Method: Protein A purified
• Test Specificity: 8E5 binds to the amino-terminal region of the beta-chain of human fibrin at an epitope consiting of GHRPLDKC. Binding is possible in both the monomeric form and the polymeric form of the protein. This peptide sequence is found only in fibrin, and not in its precursor fibrinogen and so there is no cross-reactivity with fibrinogen. Fibrin is a non-globular protein which plays a role in the clotting of blood and circulates as the precursor fibrinogen. Polymerization occurs through the action of the protease thrombin, which results in the active fibrin. Fibrin polymerizes as an insoluble matrix and forms a clot along with platelets over a wound site.