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FGIN-1-27, Tocris Bioscience™

Potent, specific ligand for mitochondrial DBI receptor

£97.39 - £312.08

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Chemical Identifiers

CAS 142720-24-9
Molecular Formula C28H37FN2O
Molecular Weight (g/mol) 436.615
InChI Key VUWXAQFLTSBUDB-UHFFFAOYSA-N
Synonym fgin-1-27, fgin 1 27, n,n-dihexyl-2-4-fluorophenyl indole-3-acetamide, fgin 1-27, n,n-di-n-hexyl-2-4-fluorophenyl indole-3-acetamide, chembl63154, 1h-indole-3-acetamide, 2-4-fluorophenyl-n,n-dihexyl, 2-2-4-fluorophenyl-1h-indol-3-yl-n,n-dihexylacetamide, tocris-0658
PubChem CID 132496
IUPAC Name 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide
SMILES CCCCCCN(CCCCCC)C(=O)CC1=C(NC2=CC=CC=C21)C3=CC=C(C=C3)F
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Description

Description

Binds specifically and with high affinity to the peptide DBI receptor (benzodiazepine receptor) on mitochondrial membranes, inducing production of neurosteroids, which modulate GABA receptors (EC50 = 3 nM for increase in production of pregnenolone in glial cells). Thus it reduces anxiety without causing sedation.
Specifications

Chemical Identifiers

142720-24-9
436.615
fgin-1-27, fgin 1 27, n,n-dihexyl-2-4-fluorophenyl indole-3-acetamide, fgin 1-27, n,n-di-n-hexyl-2-4-fluorophenyl indole-3-acetamide, chembl63154, 1h-indole-3-acetamide, 2-4-fluorophenyl-n,n-dihexyl, 2-2-4-fluorophenyl-1h-indol-3-yl-n,n-dihexylacetamide, tocris-0658
2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide
C28H37FN2O
VUWXAQFLTSBUDB-UHFFFAOYSA-N
132496
CCCCCCN(CCCCCC)C(=O)CC1=C(NC2=CC=CC=C21)C3=CC=C(C=C3)F

Specifications

142720-24-9
fgin-1-27, fgin 1 27, n,n-dihexyl-2-4-fluorophenyl indole-3-acetamide, fgin 1-27, n,n-di-n-hexyl-2-4-fluorophenyl indole-3-acetamide, chembl63154, 1h-indole-3-acetamide, 2-4-fluorophenyl-n,n-dihexyl, 2-2-4-fluorophenyl-1h-indol-3-yl-n,n-dihexylacetamide, tocris-0658
CCCCCCN(CCCCCC)C(=O)CC1=C(NC2=CC=CC=C21)C3=CC=C(C=C3)F
436.615
436.61
FGIN-1-27
C28H37FN2O
VUWXAQFLTSBUDB-UHFFFAOYSA-N
2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide
132496
>98%
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Safety and Handling

Safety and Handling

Recommended Storage : Store at Room Temperature

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