Thermo Scientific™ EZ-Link™ Sulfo-NHS-SS-Biotin and Labeling Kits

Biotinylate protein amines with this cleavable, mid-length (24.3A), water-soluble, NHS-ester biotinylation reagent containing a cleavable disulfide bond in the spacer arm.

Brand: Thermo Scientific™

Manufacturer Part Number: 21328

UNSPSC: 41115824

Code: PN

Additional Details:
Additional Details: Weight: 0.01000kg

Product Code. 10361554

Quantity Price
1 £ 137.0 / Pack of 8
EU Stock 13
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Description and Specification


Storage Requirements -20°C protected from moisture
Formulation Sulfo-NHS ester of biotin with an ethyl-1,3-dithioproprionate spacer
Cleavable Yes
Sufficient For 8 uses to label a total of 88mg of IgG using typical conditions
Molecular Weight 606.69
Spacer Arm Length 24.3
Membrane Permeable No
Description EZ-Link Sulfo-NHS-SS-Biotin, No-Weigh Format
Chemical Reactivity Amine
PEGylated No
Quantity 8 x 1mg
Water Soluble Yes


  • Cleavable analog of Sulfo-NHS-LC-Biotin
  • Can remove biotin label by cleaving spacer disulfide bond with reducing agents, such as DTT
  • Ideal for affinity purification experiments that require efficient elution from immobilized avidin supports (cleaving disulfide bond releases proteins)
  • Long spacer arm reduces steric hindrance for binding interactions


Technical documents