Thermo Scientific™ EZ-Link™ Sulfo-NHS-Biotin and Labeling Kits

Biotinylate protein amines (e.g., lysines) with our shortest (13.5A), water-soluble, NHS-ester biotinylation reagent for antibody or cell-surface labeling.

Brand: Thermo Scientific™

Manufacturer Part Number: 21217

UNSPSC: 41115824

Code: PN

Additional Details:
Additional Details: Weight: 1.81440kg

Product Code. 11851185

Quantity Price
1 £ 188.0 / 50mg
EU Stock 33
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Description and Specification


Formulation Sulfo-NHS ester of biotin
Storage Requirements -20°C with desiccant
Cleavable No
Sufficient For Approx. 25 uses to label a total of 752mg of IgG using typical conditions
Molecular Weight 443.43
Spacer Arm Length 13.5
Description EZ-Link Sulfo-NHS-Biotin
Membrane Permeable No
PEGylated No
Chemical Reactivity Amine
Quantity 50mg
Water Soluble Yes


  • Shorter spacer arm than Sulfo-NHS-LC-Biotin
  • Reacts with primary amines at pH 7-9 in non-amine-containing buffers such as borate, carbonate, or phosphate buffers
  • Negative charge of -SO3 keeps biotinylation localized at the cell surface so reagent does not pass through cell membrane
  • Water solubility eliminates the need for harmful organic solvents
U.S. Patents 5,892,628 and 5,872,261.


Technical documents