Epidermal Growth Factor Receptor (EGFR) Rabbit Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ EGFR, Rabbit Monoclonal Antibody.

Product Code	Brand	Quantity	Form
12693637	Epredia RM-2111-R7	7 mL	Ready-to-Use
12673637	Epredia RM-2111-RQ	12 mL	Ready-to-Use
12603647	Epredia RM-2111-S0	100 μL	Supernatant
12663637	Epredia RM-2111-S	1 mL	Supernatant

Description

EGFR is a type I receptor tyrosine kinase with sequence homology to c-erbB1, B2, B3, B4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-alpha (TGF-alpha), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, colon, lung, stomach, head and neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Rabbit

Clone: EP38Y

Species Reactivity: Human. Others not tested.

Ig Isotype: Rabbit IgG

Epitope: Not determined

Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr1068 of human EGFR

Molecular Weight: 175 kDa

Positive Control: Squamous carcinoma

Cellular Localization: Cell membrane and occasional cytoplasmic

Recommended for:

• Immunohistochemistry (Formalin/paraffin)

Specifications

• Clone: EP38Y
• Classification: Monoclonal
• Host Species: Rabbit
• Primary or Secondary: Primary

• Applications: Immunohistochemistry
• Conjugate: Unconjugated
• Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr1068 of human EGFR