Invitrogen™ DMAP1 Recombinant Rabbit Monoclonal Antibody (23GB5680), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA553099

Product Code. 30088987

Description

DNA methyltransferase 1-associated protein 1 (DMAP1) is involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The protein also specifically potentiates DAXX-mediated repression of glucocorticoid receptor-dependent transcription. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. DMAP1 is found in a wide variety of living organisms from yeasts to humans. The human DMAP1 gene is localized on chromosome 1p34.

Specifications

• Antigen: DMAP1
• Classification: Recombinant Monoclonal
• Conjugate: Unconjugated
• Gene: DMAP1
• Gene Alias: 1500016M21Rik; DKFZp686L09142; Dmap1; Dmtap1; DNA methyltransferase 1 associated protein 1; DNA methyltransferase 1-associated protein 1; DNMAP1; DNMT1 associated protein 1; DNMT1 associated protein-1; DNMT1-associated protein 1; DNMTAP1; EAF2; FLJ11543; KIAA1425; MAT1-mediated transcriptional repressor; MEAF2; mKIAA1425; Mmtr; RP5-891H21.2; SWC4
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 298447, 55929, 66233
• Content And Storage: -20°C
• Form: Liquid

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 23GB5680
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9JI44, Q9NPF5
• Gene Symbols: DMAP1
• Immunogen: A synthesized peptide derived from human DMAP1 (411-467AA).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG